Organic Acid Metabolite Library of Standards (OAMLS) is a collection of high quality small organic acids involved in a wide range of fundamental pathways including the tricarboxylic acid cycle, glycolysis and various physiological processes.

Cat No. OAMLS: $1,380.00

Kit Contents: Plate Map, User Manual, MLSDiscovery software tool

Preparation Instructions Compounds can either be used as standards and injected individually or a strategy may be employed to pool compounds to allow multiple mixture to be analyzed per injection. For more information, please refer to the Product Sheet.

Storage/Stability Recommended storage once solubilized at –20 °C, long-term at –80 °C; protected from moisture and light.  Avoid repeated freeze/thaw cycles.

Precautions and Disclaimer The OAMLS product is for laboratory research use only. Wear safety glass and handle with gloves. Avoid contact with skin and eyes.

Legal Information OAMLS is a trademark of IROA Technologies LLC.


Organic acid disorders and how new-born screening helps in early detection

The developments in the healthcare sector have been skyrocketing in recent years. The rising population and its demands are major contributing factors to this. But it is to be noted that lifestyles have become more demanding, and people are prone to many known and unknown health complications in this modern age. Moreover, infants and senior adults are at high risk of suffering from chronic diseases due to low immunity and energy levels.

The human body is effectively a very efficient complex chemical factory.  Various acids, enzymes, and other chemical compounds work together in perfect coordination to facilitate the different life processes that keep a human alive. The human body processes produce organic acids such as lactic, and citric acids, etc and they can be found in urine and blood. But what are organic acid metabolites? This informative piece will introduce you to the different types of related organic acid metabolite disorders and how early infant screening can be beneficial. Read along to find out more.

What are organic acid metabolites disorders?

Organic acid metabolites disorder refers to a medical situation in which organic acids accumulate in the blood and urine. As these metabolites can be toxic, abnormal levels can cause severe health complications over time. It is an inherited type of condition caused by the deficiency of certain enzymes in the body. These disorders are mainly found in infants, and if not tested in time, the severity of the situation may worsen. Hence, when attending physicians or parents see specific differences in the behavior and health of an infant, instant screening should be considered. Some of the common symptoms in infants include

  • Fatigue
  • Vomiting
  • Seizures
  • Weakness
  • Poor feeding etc.

If left unattended, the disorder can even cause the infant to go into a coma. Moreover, if the treatment is not effective, the patient might be at the risk of losing their lives in the process. It is why immediately after a screen positive result, the doctor and parents should take immediate action. Hence, after checking the current status of the baby, one needs to refer a metabolic disease specialist to follow on with proper treatment.

Some possible treatment and advice for parents

If the screening is done correctly and one takes the proper steps, then the infant can be safe. Apart from prescribed medications, one needs to take extreme nutritional care of the infant’s diet. The doctor may recommend carnitine supplements and a low protein diet for the baby. Apart from this, some doctors even recommend glucose administration as well.

In difficult situations, it is up to the parents and the doctors to save the infant. The parents need to stay calm and not panic about the situation. The infant’s condition will get back to normal with the proper medications. It is recommended that parents attend genetic counseling sessions to help with disease awareness and their own mental stability.

The information provided above regarding organic acid metabolites disorders can be a helpful guide for those looking for a simplified version of this biological issue. It is by no means exhaustive and it is important to seek medical attention as needed. It is also important to note that this disorder may manifest itself at birth, or even later in life as an adult. Most disorders and diseases can be cured using the latest medical care and technology.

Practicing healthy lifestyle rituals such as a balanced diet and exercise regime in one’s routine can help lower the risk of falling into the shackles of such health complications. And as far as the organic acid metabolites disorders are concerned, on-time screening and proper treatment can contribute to the healthy life of the suffering patient.