ROUTINELY IDENTIFIED COMPOUNDS IN INTERNAL STANDARD
USER MANUAL
POSTER – Correction of Ion Suppression and Normalization for Improved Quantitative Rigor and Reproducibility using IROA
WHITEPAPER – Integration of Standards for Ion Suppression Correction and QC in an Untargeted Metabolomics Workflow
How to set up and run a C13-labeled Yeast Extract “TruQuant” Calibration Experiment
TruQuant Workflow References:
Charkoftaki, G., Aalizadeh, R., Santos-Neto, A. et al. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Hum Genomics 17, 80 (2023). https://doi.org/10.1186/s40246-023-00521-4
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Habet V, Li N, Qi J, et al. Integrated Analysis of Tracheobronchial Fluid from Before and After Cardiopulmonary Bypass Reveals Activation of the Integrated Stress Response and Altered Pulmonary Microvascular Permeability. The Yale Journal of Biology and Medicine. 2023 Mar;96(1):23-42. DOI: 10.59249/kfyz8002. PMID: 37009190; PMCID: PMC10052603.
Piqueras, M.D.C., Myer, C., Junk, A., Bhattacharya, S.K. (2019). Isotopic Ratio Outlier Analysis (IROA) of Aqueous Humor for Metabolites. In: Bhattacharya, S. (eds) Metabolomics. Methods in Molecular Biology, vol 1996. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9488-5_15
Qiu Y, Moir RD, Willis IM, Seethapathy S, Biniakewitz RC, Kurland IJ. Enhanced Isotopic Ratio Outlier Analysis (IROA) Peak Detection and Identification with Ultra-High Resolution GC-Orbitrap/MS: Potential Application for Investigation of Model Organism Metabolomes. Metabolites. 2018 Jan 18;8(1):9. doi: 10.3390/metabo8010009. PMID: 29346327; PMCID: PMC5875999.