Metabolomics Tools

Mass Spectrometry Metabolite Library of Standards (MSMLSTM) supplied with software tool MSMLSDiscoveryTM

Over 600 high quality primary metabolite standards provided in convenient 96 well format. MSMLSDiscovery is a software tool designed to help build authentic standard libraries for MS and supports the extraction, manipulation, and stoarge of the date generated when using MSMLS.

IROA Biochemical Quantitation Kit Catalog #300-250 (for Mammalian cells)

Like SILAC, IROA utilizes full metabolic labeling to distinguish between two mammalian cell populations but uses both 5% 13C (experimental samples) and 95% 13C (control samples) to remove artifacts/noise, calculate carbon number and molecular formula  to enable metabolite identification.


News & Events

New Publication!

Isotopic Ratio Outlier Analysis (IROA) of the S. cerevisiae metabolome using accurate mass GC-TOF/MS: A new method for discovery

Yunping Qiu 1, Robin Moir 1,  Ian M.Willis 1, Chris Beecher 2,  Yu-Hsuan Tsai 1, Timothy J. Garrett 3  Richard A. Yost  3, Irwin Jack Kurland 1
1 Albert Einstein College of Medicine, Bronx, NY, USA,  2 IROA Technologies LLC, Ann Arbor, MI, USA, 3 University of Florida, Gainesville, FL, USA 


ASMS and Metabolomics 2016

We hope to see you at the following poster presentations:


Mon, June 6 

  1. Abstract ID number: 279546  Study of Untargeted Metabolite Degradation in Plasma using Isotopic Ratio Outlier Analysis by uHPLC-HRMS
  2. Abstract ID number: 282364  Using Isotopic Ratio Analysis (IROA) and Non-negative Matrix Factorization (NMF) to sort mixtures in metabolomic analyses

Tue, June 7

  1. Abstract ID number: 282782  Isotopic Ratio Outlier Analysis (IROA) global metabolome interrogation of an actinomycete bacterium following introduction of a novel pathway
Thurs, June 9
  1. Abstract ID number: 278554  Metabolic Profiling of Type 1 Diabetes From Primary and Established T Cells Using Isotopic Ratio Outlier Analysis by LC-MS

Metabolomics Conference 2016

We hope to see you at the following poster presentations:

Title:  IROA Fluxomic analyses: a non-targeted, all-encompassing protocol using IROA (Isotopic Ratio Outlier Analysis)

Presenting Author: Chris Beecher

Date/time: TBD 

Title:  Identification of LC-MS metabolite fragments using IROA (Isotopic Ratio Outlier Analysis)

Presenting Author: Felice de Jong

Date/time: TBD